ACCESS Newswire
13 Jun 2019, 18:01 GMT+10
Research findings may provide deeper understanding on the role of genes that can contribute to development of Hypophosphatasia
CAMBRIDGE, MA and ROSTOCK, GERMANY / ACCESSWIRE / June 13, 2019 / CENTOGENE today announced a new research study to identify genetic variants in patients with hypophosphatasia (HPP). The one year multicentric research study will be conducted in Rostock, Germany and Bogota, Colombia.
'We are excited to be leveraging our genetic expertise and knowledge to further identify and better understand the genetic mutations that play a role in the clinical spectrum of HPP,' said Dr. Arndt Rolfs, CEO CENTOGENE. 'We are deeply committed to bringing hope to patients and their families by shortening the diagnostic odyssey, and we are proud to be working on this important study to better understand mutations in the ALPL gene. We are focused on leveraging the insights gained from this research to help to accelerate the diagnosis of our patients.'
HPP is an inherited rare metabolic disease that is characterized by low tissue-nonspecific activity of the enzyme alkaline phosphatase (ALP), which plays an essential role in bone and teeth building and maintenance. Known pathogenic variants in the ALPL gene lead to HPP, however, an unknown percentage of clinically diagnosed HPP patients do not carry ALPL pathogenic variants. The research is designed to identify mutations in genes that may cause a phenocopy of HPP and therefore being mixed up or not diagnosed.
About CENTOGENE
CENTOGENE is a rare disease company focused on transforming clinical, genetic, and biochemical data into medical solutions for patients. We are focused on bringing rationality to treatment decisions and accelerating the development of new orphan drugs by using our knowledge of the global rare disease market, including our epidemiological and clinical heterogeneity and our innovative biomarkers.
As one of the largest rare disease companies worldwide, CENTOGENE is dedicated to transforming the science of genetic information into solutions and creating hope for our patients with rare diseases and their families.
CENTOGENE AG
Ross Bethell
Director, Corporate Communications
[email protected]
SOURCE: CENTOGENE AG
Get a daily dose of Atlanta Leader news through our daily email, its complimentary and keeps you fully up to date with world and business news as well.
Publish news of your business, community or sports group, personnel appointments, major event and more by submitting a news release to Atlanta Leader.
More InformationDOVER, Delaware: California Governor Gavin Newsom has taken legal aim at Fox News, accusing the network of deliberately distorting...
FRANKFURT, Germany: Germany has become the latest country to challenge Chinese AI firm DeepSeek over its data practices, as pressure...
TORONTO, Canada: Harvard University and the University of Toronto have created a backup plan to ensure Harvard graduate students continue...
JERUSALEM, Israel: Israeli Prime Minister Benjamin Netanyahu says that Israel's success in the war with Iran could open the door to...
NEW DELHI, India: India has decided not to allow a United Nations (UN) investigator to join the investigation into the recent Air India...
BONN, Germany: Despite widespread belt-tightening across the United Nations, nearly 200 countries agreed this week to increase the...
NEW YORK, New York - U.S. stock markets closed firmly in positive territory to start the week Monday, with the S&P 500 and Dow Jones...
WASHINGTON, D.C.: On Friday, President Donald Trump announced that he was halting trade discussions with Canada due to its decision...
LONDON, U.K.: A little-known investment fund based in the United Arab Emirates has emerged as the most prominent public backer of U.S....
SAN FRANCISCO, California: Across the U.S., a growing number of people are taking obesity treatment into their own hands — literally....
SAN FRANCISCO, California: Under pressure from European regulators, Apple has revamped its App Store policies in the EU, introducing...
NEW YORK CITY, New York: The U.S. dollar tumbled this week, hitting its lowest levels since 2021 against the euro, British pound, and...